2-Chlorotritylchloride Resin – An extremely versatile, acid-labile resin

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Purchase Q83067785

5g $40.00
25g $145.00
100g $445.00

"An extremely versatile, acid-labile resin for the solid phase immobilization of carboxylic acids, alcohols, phenols and amines, imidazoles and hydroxylamines. Release of these functionalities is generally achieved using 1-50% TFA in DCM containing 5% TIS, although carboxylic acids can also be cleaved from this support with AcOH/TFE/DCM, 0.5% TFA in DCM, or HFIP in DCM. 2-Chlorotrityl chloride resin can be cleaved under extremely mild acid conditions that leave Boc/tBu based protecting groups in place. Thus it is used to prepare protected peptide fragments. Amino acids can be attached to 2-Cl-Trt chloride resin with very little or no racemization. The steric bulk of 2-chlorotrityl chloride resin inhibits diketopiperazine formation, which can be a major side reaction in the synthesis of peptides with C-terminal proline." See prices below.

PubChem Compound Summary

Catalog Number SC5055
InChIKey JFLSOKIMYBSASW-UHFFFAOYSA-N
SureChEMBL ID SCHEMBL26214
Human Metabolome Database ID HMDB0245082
Canonical SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)Cl
Chemical Formula C₁₉H₁₄Cl₂
PubChem CID 94524
DSSTOX Compound Identifier DTXCID00117405
Instance Of type of chemical entity
Mass 312.047255808
DSSTox Substance ID DTXSID60194914
InChI InChI=1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H
UNII GG3RF829XL
UniChem Compound ID 11079217
Subclass Of chemical compound
CAS Registry Number 42074-68-0

2-Chlorotritylchloride Resin – An extremely versatile, acid-labile resin

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2-Chlorotritylchloride Resin – An extremely versatile, acid-labile resin Depositor-Supplied Synonyms

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2-Chlorotritylchloride Resin – An extremely versatile, acid-labile resin R3D Conformer

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2-Chlorotritylchloride Resin – An extremely versatile, acid-labile resin GHS Classification

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