Fmoc-Gln(Trt)-OH – Dissolves readily in peptide synthesis reagents
Purchase Fmoc-Gln(Trt)-OH; Nalpha-Fmoc-Ndelta-trityl-L-glutamine; 132327-80-1
View Safety Data Sheet (SDS)
| 5g | $25.00 |
| 25g | $55.00 |
| 100g | $165.00 |
Fmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln [1]. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp. Using Fmoc-Gln(Trt)-OH in peptide synthesis prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Gln(Trt)-OH also has better solubility properties than Fmoc-Gln-OH. Fmoc-Gln(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Gln-OH is much less soluble in dimethylformamide (DMF). See prices below.
| Catalog Number | FQ2251 |
| Subclass Of | chemical compound |
| UniChem Compound ID | 24268718 |
| CAS Registry Number | 132327-80-1 |
| Mass | 610.246772188 |
| Chemical Formula | C₃₉H₃₄N₂O₅ |
| EC Number | 603-564-1 |
| PubChem CID | 10919157 |
| Isomeric SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)CC[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46 |
| Canonical SMILES | O=C(CCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)NC(c1ccccc1)(c1ccccc1)c1ccccc1 |
| InChIKey | WDGICUODAOGOMO-DHUJRADRSA-N |
| InChI | InChI=1S/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)25-24-35(37(43)44)40-38(45)46-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34/h1-23,34-35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t35-/m0/s1 |
| ECHA Substance Infocard ID | 100.109.682 |
| UNII | D96P722NZE |
| DSSTox Substance ID | DTXSID70448258 |
| SureChEMBL ID | SCHEMBL120503 |
| Instance Of | type of chemical entity |
| DSSTOX Compound Identifier | DTXCID70399079 |
| Stereoisomer Of | N-Fmoc-N'-trityl-D-glutamine |
Fmoc-Gln(Trt)-OH – Dissolves readily in peptide synthesis reagents
Fmoc-Gln(Trt)-OH – Dissolves readily in peptide synthesis reagents Related Compounds with Annotation
Fmoc-Gln(Trt)-OH – Dissolves readily in peptide synthesis reagents Depositor-Supplied Synonyms
Fmoc-Gln(Trt)-OH – Dissolves readily in peptide synthesis reagents R3D Conformer
Fmoc-Gln(Trt)-OH – Dissolves readily in peptide synthesis reagents GHS Classification
Buy Fmoc-Gln(Trt)-OH; Nalpha-Fmoc-Ndelta-trityl-L-glutamine; 132327-80-1 online.
