Fmoc-Glu(OBut)-OH – Standard Fmoc-protected derivatives of Glu

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Purchase Fmoc-Glu(OBut)-OH; Fmoc-L-glutamic acid 5-tert-butyl ester; 71989-18-9

5g $20.00
25g $45.00
100g $135.00

Fmoc-Glu(OtBu)-OH is the standard Fmoc-protected derivatives of Glu used in peptide synthesis. The t-butyl ester of the side chain is removed in the same conditions used to cleave peptides from Wang resin or Rink amide resin. The t-butyl cations formed in the hydrolysis of the ester can produce byproducts by reattaching to nucleophilic residues in the peptide, so nucleophilic scavengers such as thiophenol and anisole should be added to the cleavage mixture when Fmoc-Glu(OtBu)-OH are utilized. See prices below.

PubChem Compound Summary

Catalog Number FE2237
Mass 425.18383758400006
Isomeric SMILES CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
UniChem Compound ID 22798701
EC Number 688-911-5
Chemical Formula C₂₄H₂₇NO₆
InChIKey GOPWHXPXSPIIQZ-FQEVSTJZSA-N
Subclass Of 5-tert-Butyl N-((9H-fluoren-9-ylmethoxy)carbonyl)-2-aminoglutarate
ECHA Substance Infocard ID 100.215.639
Instance Of type of chemical entity
DSSTox Substance ID DTXSID80426921
InChI InChI=1S/C24H27NO6/c1-24(2,3)31-22(28)20(12-13-21(26)27)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,27)/t20-/m0/s1
UNII XXH3RHN4GT
PubChem CID 7017912
DSSTOX Compound Identifier DTXCID10377755
Canonical SMILES CC(C)(C)OC(=O)C(CCC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21
CAS Registry Number 84793-07-7
SureChEMBL ID SCHEMBL1709129

Fmoc-Glu(OBut)-OH – Standard Fmoc-protected derivatives of Glu

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Fmoc-Glu(OBut)-OH – Standard Fmoc-protected derivatives of Glu Depositor-Supplied Synonyms

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Fmoc-Glu(OBut)-OH – Standard Fmoc-protected derivatives of Glu R3D Conformer

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Fmoc-Glu(OBut)-OH – Standard Fmoc-protected derivatives of Glu GHS Classification

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