HBTU – Aminium-based Coupling Reagent for Peptide Synthesis

HBTU would be the most employed aminium-based coupling reagent in peptide synthesis due to its low cost, excellent activation, racemization suppression, and good solubility and stability. HBTU normally is used in combination with a base like diisopropylethyl amine.

Catalog Number	RC8106
CAS Number	94790-37-1
Molecular Weight	379.25g/mole
Formula	C11H16F6N5OP

HCTU – Creates New Peptides and Bonds

HCTU is an aminium coupling reagent used during the process of peptide synthesis. Peptide synthesis is important within chemistry, allowing us to create new peptides and bonds (this is the backbone of proteins). HCTU is available in three catalog sizes: 25g, 100g or 250g, but also good for bulk quantity.

Catalog Number	RC8116
CAS Number	330645-87-9
Molecular Weight	413.69 g/mole
Formula	C11H15CLF6N5OP

HDBTU

Catalog Number	RC6090
CAS Number	164861-52-3
Molecular Weight	407.25 g/mol
Formula	C12H16F6N5O2P
Synonym	2-(3,4-Dihydro-4-oxy-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N,N,N',N'-TetraMethyl-O-(4-oxo-3,4-dihydro-1,2,3-benzotriazin-3-yl)uronium hexafluorophosphate

HDMA

Catalog Number	RC8701
CAS Number	958029-37-3
Molecular Weight	422.27 g/mole
Formula	C12H17F6N6O2P

HFIP, Hexafluoroisopropanol

Catalog Number	RA8406
CAS Number	920-66-1
Molecular Weight	168.04 g/mole
Formula	C3H2F6O
Synonym	1,1,1,3,3,3-Hexafluoro-2-propanol

HMBA Linker, 4-(Hydroxymethyl)benzoic acid

Catalog Number	RT1035
CAS Number	3006-96-0
Molecular Weight	152.15g/mole
Formula	C8H8O3

HNTU

Catalog Number	RC6095
CAS Number	208462-94-6
Molecular Weight	423.30 g/mol
Formula	C14H20F6N3O3P
Synonym	O-(endo-5-Norbornene-2,3-dicarboximido)-N,N,N',N'-tetramethyluronium hexafluorophosphate; 2-(Endo-5-norbornene-2,3-dicarboxymido)-1,1,3,3-tetramethyluronium hexafluorophosphate

HOBt Hydrate – benzotriazole derivative to improve the efficiency of peptide synthesis

1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.

Catalog Number	RC8201
CAS Number	123333-53-9
Molecular Weight	135.13·18.02g/mole
Formula	C6H5N3O·H2O
Synonym	1-Hydroxybenzotriazole monohydrate

HOCT

Catalog Number	RC6135
CAS Number	137156-41-3
Molecular Weight	157.13 g/mol
Formula	C5H7N3O3
Synonym	Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate; 1-Hydroxy-1H-1,2,3-triazole-5-carboxylic acid ethyl ester

HONB

Catalog Number	RC6100
CAS Number	21715-90-2
Molecular Weight	179.17 g/mol
Formula	C9H9NO3
Synonym	N-Hydroxy-5-norbornene-2,3-dicarboxylic acid imide; N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid imide; N-hydroxynorborn-5-ene-2,3-dicarboximide; endo-N-Hydroxy-5-norbornene-2,3-dicarboximide

HONp

Catalog Number	RC8203
CAS Number	100-02-7
Molecular Weight	139.11g/mole
Formula	C6H5NO3

HOOBT

Catalog Number	RC6105
CAS Number	28230-32-2
Molecular Weight	163.13 g/mol
Formula	C7H5N3O2
Synonym	3-Hydroxy-1,2,3-benzotriazin-4(3H)-one; DHOBT; hydroxy-3,4-dihydro-4-oxo-1,2,3-benzotriazine; 3,4-Dihydro-3-Hydroxy-oxo-1,2,3-Benzotriazine

HOPO

Catalog Number	RC6265
CAS Number	13161-30-3
Molecular Weight	111.10 g/mol
Formula	C5H5NO2
Synonym	2-Pyridinol 1-oxide; 1-Hydroxy-2-pyridone; 2-Hydroxypyridine 1-oxide

HOSu

Catalog Number	RC8302
CAS Number	6066-82-6
Molecular Weight	115.09g/mole
Formula	C4H5NO3

HOTT

Catalog Number	RC6130
CAS Number	212333-72-7
Molecular Weight	371.28 g/mol
Formula	C10H16F6N3OPS
Synonym	S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuronium hexafluorophosphate; N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate; S-(2-Pyridyl)-N,N,N',N'-tetramethylthiuronium N-oxide hexafluorophosphate

HOTU

Catalog Number	RC6075
CAS Number	333717-40-1
Molecular Weight	386.23 g/mol
Formula	C10H17F6N4O3P
Synonym	O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate;

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