Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid

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Purchase Fmoc-Asp(OBut)-OH; Fmoc-L-Aspartic acid beta-tert-butyl ester; 71989-14-5

5g $20.00
25g $35.00
100g $105.00

Fmoc-Asp(OtBu)-OH is the standard Fmoc-protected derivative of aspartic acid used in peptide synthesis. The t-butyl ester of the side chain is readily hydrolyzed in the same conditions used to cleave peptides from Wang resin or Rink amide resin. The t-butyl cations formed in the hydrolysis of the esters can produce byproducts by reattaching to nucleophilic residues in the peptide, so nucleophilic scavengers such as thiophenol and anisole should be added to the cleavage mixture when Fmoc-Asp(OtBu)-OH is utilized. See prices below.

PubChem Compound Summary

Catalog Number FD2192
SureChEMBL ID SCHEMBL872021
PubChem CID 2724635
Canonical SMILES CC(C)(C)OC(=O)CC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O
Isomeric SMILES CC(C)(C)OC(=O)C[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Instance Of type of chemical entity
CAS Registry Number 71989-14-5
UNII JHQ6MY724T
Chemical Formula C₂₃H₂₅NO₆
UniChem Compound ID 24152872
InChI InChI=1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
InChIKey FODJWPHPWBKDON-IBGZPJMESA-N
Mass 411.16818752000006
Subclass Of chemical compound

Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid

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Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid Depositor-Supplied Synonyms

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Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid R3D Conformer

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Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid GHS Classification

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