Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid

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Purchase Fmoc-Asp(OBut)-OH; Fmoc-L-Aspartic acid beta-tert-butyl ester; 71989-14-5

5g $20.00
25g $35.00
100g $105.00

Fmoc-Asp(OtBu)-OH is the standard Fmoc-protected derivative of aspartic acid used in peptide synthesis. The t-butyl ester of the side chain is readily hydrolyzed in the same conditions used to cleave peptides from Wang resin or Rink amide resin. The t-butyl cations formed in the hydrolysis of the esters can produce byproducts by reattaching to nucleophilic residues in the peptide, so nucleophilic scavengers such as thiophenol and anisole should be added to the cleavage mixture when Fmoc-Asp(OtBu)-OH is utilized. See prices below.

PubChem Compound Summary

Catalog Number FD2192
PubChem CID 2724635
Isomeric SMILES CC(C)(C)OC(=O)C[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Instance Of type of chemical entity
CAS Registry Number 71989-14-5
Chemical Formula C₂₃H₂₅NO₆
InChI InChI=1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
InChIKey FODJWPHPWBKDON-IBGZPJMESA-N
Instance Of chemical compound

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Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid

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Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid Depositor-Supplied Synonyms

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Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid R3D Conformer

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Fmoc-Asp(OBut)-OH – standard Fmoc-protected derivative of aspartic acid GHS Classification

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